How would you allocate $1-10m personally towards maximising progress? Would a FRO or PARPA be the right choice over say angel investing in startups or funding smaller research projects?

Sounds awesome, agree! 

Which research areas would you be most excited to support to accelerate progress (energy comes to mind, open to many more for funding via https://www.molecule.to/ and https://www.bio.xyz/), and which "applied metascience" seems most useful beyond new institutions for funding r&d such as PARPA, FROs? 

Excited for this, great idea to bring the discussion together in one place. 

How would you allocate $10 million to create the most positive long-term progress?