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Marc Andreessen pens “Techno-Optimist Manifesto.” Discuss

the Precautionary Principle is objectively bad:

You might want to Ctrl+F here for mentions of the precautionary principle: https://www.sciencedirect.com/science/article/pii/S0169207020301230 

1jasoncrawford10moThanks. What I see is that this paper specifies “a non-naive precautionary principle” or “an intelligent application of the precautionary principle,” which implies something about what the precautionary principle might end up being in practice without those qualifiers…
Marc Andreessen pens “Techno-Optimist Manifesto.” Discuss

E.g., "Our enemy is the Precautionary Principle", unqualified

3jasoncrawford1yTo be exact, what he said was: I interpret that to mean not that he's against precaution, but that he thinks terms like that are being used to promote bad ideas. Also, the Precautionary Principle is objectively bad: –David Deutsch, The Beginning of Infinity –Matt Ridley, How Innovation Works
Marc Andreessen pens “Techno-Optimist Manifesto.” Discuss

I see the appeal and I like the aliveness, but I dislike the lack of nuance and disagree on the specifics.

1jasoncrawford1yWhich specifics?
AMA: Allison Duettmann, Foresight Institute

Do you see most of the value/impact/benefit that the Foresight Institute produces as coming from a few key outputs, or from a larger list of projects each of which only produces a fraction of your total value? If the first, what are your key outputs?

4AllisonDuettmann1yI think Foresight's value comes from a larger list of projects each of which has a small chance at creating a large impact. This comes mostly from the fact that we focus on advancing the beneficial use of a variety of undervalued technologies, including nano, bio, neuro, computing, and space, whose trajectory is harder to predict. We do this through early ecosystem development in these areas, that usually includes tools like our fellowships, prizes, workshops, and virtual seminars. Given that different technologies impact Given that many of the technologies are influenced by the relative speed of other technologies, they will be advancing at varying rates, and tools to accelerate them are differently useful at different stages. For instance, for driving progress in Molecular Nanotechnology, from 1986 onward, Foresight started hosting annual technical conferences, published research papers, developed a Nanotechnology Roadmap, and launched the Feynman Prizes to award work toward molecular manufacturing. The road was incredibly bumpy, but in 2016, Sir Fraser Stoddart was finally awarded the Nobel Prize for his work “for the design and synthesis of molecular machines” (https://www.nobelprize.org/prizes/chemistry/2016/press-release/ [https://www.nobelprize.org/prizes/chemistry/2016/press-release/]) just nine years after he received Foresight’s Feynman Prize [https://foresight.org/foresight-feynman-prizes/] for the exact work: https://foresight.org/foresight-feynman-prizes/ [https://foresight.org/foresight-feynman-prizes/] Today, molecular nanotechnology progress is accelerating faster, largely enabled by new AI simulation tools, such as AlphaFold, Rosetta, Samson, CanDo, and more. Simulation tools, combined with progress in newer approaches to molecular nanotechnology, such as DNA origami, led tech-analysts such as Eli Durado declare that it’s Nanotechnology’s spring: https://worksinprogress.co/issue/nanotechnologys-spring To streamline progress across tool builders
AMA: Allison Duettmann, Foresight Institute

What does Eric Drexler think about the Foresight Institute? If I recall correctly, he was one of the founders?

5AllisonDuettmann1yI think this is a question that is better directed at Eric himself :) I can confirm that he was one of Foresight’s co-founders, and that he did present at a few more Foresight recent events, such as the Decentralized AI workshop ( https://www.youtube.com/watch?v=pClSjljMKeA [https://www.youtube.com/watch?v=pClSjljMKeA], https://www.youtube.com/watch?v=hNDD-ZbEsJA) and a Molecular Machines workshop (https://www.youtube.com/watch?v=HjgjtAk-lws&t=1s). I can also definitely say that our community remains excited about his outstanding work, such as Comprehensive AI Services, the Open Agency Architecture, Paretotopian Goal Alignment, and Molecular Nanotechnology.
AMA: Allison Duettmann, Foresight Institute

What are some example decisions that the Foresight Institute's work has helped influence?

4AllisonDuettmann1yGiven that our main effort is to kindle beneficial innovation in undervalued technical domains of importance for the long-term future, such decisions are sometimes hard to trace but are mostly in the area of founding and funding such projects. Through Foresight matchmaking, members have started companies (such as a carbon drawdown company co-founded by a Foresight Fellow who met their co-founder at a Foresight event and recently raised $30M in follow-on funding), new research projects (such as a major research project building LLM-enabled preference simulations of groups of people which was founded and funded at a Foresight workshop), and existing organizations receiving government funding (more than $30M for a water filtration company, and $15M for a molecular nanotechnology simulation project at a university through Foresight workshops). Other decisions we shape involve early career path choices, with individuals joining organizations, including a neurotech FRO, several major longevity companies, and security companies, through Foresight events. In rare cases, aid career decisions more actively, for instance by providing J1 visas to promising researchers seeking to move to the US. This more tailored support is particularly prominent with younger applicants who have little default exposure to senior researchers, funders, and entrepreneurs in their domain.
Introductions thread (please introduce yourself)

I'm Nuño Sempere, a researcher at the Quantified Uncertainty Research Institute, where I work on refining broadly utilitarian estimation methods. I have a blog here—where I post my research but also offer cancellation insurance or talk abou the joys of programming a browser in C—and a forecasting newsletter here. I learnt about this place through EA (effective altruism), which I've become a bit disillusioned about.

Eli Dourado AMA

For a center hosted by a university, what cut of funding does the university normally take?

1elidourado2yI am blessedly exempt from having to deal with any financial or management issues at the CGO, so I don't know. We do get along with the USU administration really well, though.